A sixteen year-old boy Krtin Nithiyanadam, who had moved to United Kingdom with his parents, claimed to have found the solution on most deadly form of breast cancer which is also unresponsive to drugs.

Krtin claims that he has found a way to make, famous triple negative breast cancer respond to drugs.

A famous daily of the country reported Krtin as saying, “I've been basically trying to work out a way to change difficult-to-treat cancers into something that responds well to treatment. Most cancers have receptors on their surface which bind to drugs like Tamoxifen but triple negative don't have receptors so the drugs don't work.”

“The prognosis for women with undifferentiated cancer isn't very good so the goal is to turn the cancer back to a state where it can be treated. The ID4 protein actually stops undifferentiated stem cell cancers from differentiating so you have to block ID4 to allow the cancer to differentiate,” he said.

Krtin added, “I have found a way to silence the genes that produce ID4 which turns cancer back into a less dangerous state.”

While some women do respond to the triple negative cancer, others quickly declines. The problem, according to experts, lies in whether the triple negative cancer cells are differentiated or not.

Differentiated cells looks healthy, tend to grow and multiply quite slowly and are less aggressive. On the other side, undifferentiated cancer cells get stuck in dangerous primitive form, they multiply quickly and leads to high grade tumors.

Krtin has said that upping the activity of a tumor-suppressor gene called PTEN allows chemotherapy to work more effectively. This dual treatment can prove more effective than traditional drugs, according to Krtin.

Earlier, Krtin came under the spotlight when he won the Google Science Fair for creating a test which helps in picking up early signs of Alzheimer’s and potentially stops it from spreading further.

By Prajakt K.