Multipurpose Protein Can Be Effective In Alzheimer’s Disease Treatment: Researchers

August 31, 2016 17:29
Multipurpose Protein Can Be Effective In Alzheimer’s Disease Treatment: Researchers

According to the researchers, protein can be helpful in reversing the effects of damaging plaques in the brain associated with Alzheimer’s disease. This finding is step closer to a successful treatment of the disease.

According to the experts, the accumulation in the brain of plaques formed from deposits of a critical protein, knows as amyloid beta, is a main sign of the Alzheimer’s disease.

The researchers said that the multipurpose protein known as p62, regulates the degradation or turnover of amyloid beta in living systems, which may help reverse the effects of damaging plaques in the brain.

A researcher, Salvatore Oddo from Arizona State University in the US said, “These exciting finding suggest that compounds aimed at increasing p62 may have beneficial effects for Alzheimer's disease.”

Alzheimer’s, which does not have effective therapy currently, is a deadly disease which kills the nerve cells and tissues throughout the brain.

The disease also caused brain to be shrink dramatically which affects about all its functions.

The Study shows that the improvement is associated with reduced levels of amyloid beta and associated plaques in the brain. It also explained the new mechanism by which p62 activity improves Alzheimer’s disease symptoms in mice, by a process known as Authophagy, a term refers to the degradation or disassembly of unnecessary or dysfunctional components of cell, a biological recycling form which is essential in cellular health.

By Prajakt K.

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